Friday - June 1, 2018
Not intended for U.S. and UK Media - Translational research and clinical development collaboration:

Bayer and MD Anderson Cancer Center to collaborate on development of novel cancer treatments

5-year agreement to accelerate early clinical development of selected Bayer drug candidates / Collaboration part of Bayer’s focused segment leadership strategy in oncology

Berlin, June 1, 2018 – Bayer and the University of Texas MD Anderson Cancer Center have signed a five-year collaboration agreement to accelerate the development of novel targeted treatments based on patient or tumor characteristics for which current therapies have not shown satisfactory clinical efficacy. Bayer will contribute early stage as well as clinical assets from its development pipeline for further clinical development at MD Anderson Cancer Center. The MD Anderson Cancer Center will bring in its translational and clinical expertise to help accelerate ongoing and future clinical trials.

“Bayer is committed to translating the science of cancer research into new innovative treatment options for patients who are in need”, said Robert LaCaze, Member of the Executive Committee of Bayer AG’s Pharmaceuticals Division and Head of the Oncology Strategic Business Unit at Bayer. “The alliance with MD Anderson will bolster our ongoing and future clinical programs with the overall aim of developing meaningful innovations for patients battling cancer.”

Bayer focuses its oncology research on key areas of investigation, including immuno-oncology, oncogenic signaling, and targeted thorium conjugates, and seeks a precision medicine approach where applicable to develop targeted treatment regimens based on patient or tumor characteristics. As part of the company’s overall innovation strategy, Bayer is expanding discovery and development opportunities through a series of strategic agreements with leading academic centers, other pharmaceutical companies and innovative biotech organizations worldwide. With the collaboration with MD Anderson, Bayer is further strengthening its development activities in oncology, particularly in translational and clinical development.

The MD Anderson Cancer Center ranks as one of the world’s most respected centers focused on research and cancer patient care. MD Anderson’s expertise and knowledge in oncology and clinical research is complementing Bayer’s experience in pharmaceutical development. Bayer’s goal is to significantly broaden the applicability of breakthrough approaches – specifically in cancer indications and tumors where current therapies have not shown clinical efficacy.

“MD Anderson is committed to advancing new therapies that can be offered more quickly to our patients,” said Patrick Hwu, M.D., division head, Cancer Medicine Administration at MD Anderson. “This collaboration allows us to pursue the study of several investigative agents that may have potential for cancers that can be resistant to standard treatments.”

The joint clinical research projects will be conducted at the MD Anderson Cancer Center in Houston, Texas. Financial terms of the agreement were not disclosed.

About MD Anderson Cancer Center
The University of Texas MD Anderson Cancer Center in Houston ranks as one of the world's most respected centers focused on cancer patient care, research, education and prevention. The institution’s sole mission is to end cancer for patients and their families around the world. MD Anderson is one of only 49 comprehensive cancer centers designated by the National Cancer Institute (NCI). MD Anderson is ranked No.1 for cancer care in U.S. News & World Report’s “Best Hospitals” survey. It has ranked as one of the nation’s top two hospitals for cancer care since the survey began in 1990, and has ranked first 13 times in the last 16 years. MD Anderson receives a cancer center support grant from the NCI of the National Institutes of Health (P30 CA016672).

About Oncology at Bayer
Bayer is committed to delivering science for a better life by advancing a portfolio of innovative treatments. The oncology franchise at Bayer now includes four oncology products and several other compounds in various stages of clinical development. Together, these products reflect the company’s approach to research, which prioritizes targets and pathways with the potential to impact the way that cancer is treated.

About Bayer
Bayer is a global enterprise with core competencies in the Life Science fields of health care and agriculture. Its products and services are designed to benefit people and improve their quality of life. At the same time, the Group aims to create value through innovation, growth and high earning power. Bayer is committed to the principles of sustainable development and to its social and ethical responsibilities as a corporate citizen. In fiscal 2017, the Group employed around 99,800 people and had sales of EUR 35.0 billion. Capital expenditures amounted to EUR 2.4 billion, R&D expenses to EUR 4.5 billion. For more information, go to www.bayer.com.

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Forward-Looking Statements
This release may contain forward-looking statements based on current assumptions and forecasts made by Bayer management. Various known and unknown risks, uncertainties and other factors could lead to material differences between the actual future results, financial situation, development or performance of the company and the estimates given here. These factors include those discussed in Bayer’s public reports which are available on the Bayer website at www.bayer.com. The company assumes no liability whatsoever to update these forward-looking statements or to conform them to future events or developments.

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